Gona-Max or Human Chorionic Gonadotropin (abbreviated HCG) is formed exclusively in the placenta of a pregnant woman, being a natural hormone. It is produced in the laboratory from the urine of a woman during pregnancy. Its effect on humans is similar to that of luteinizing hormone, the forerunner of testosterone.
The use of the drug orally ineffective, as evidenced by numerous studies. Experiments conducted in the United States proved the complete failure of food additives containing human chorionic gonadotropin. In addition, in the United States there is a ban on the use of this substance.
HCG effects
By its effect on the body, Human Chorionic Gonadotropin is completely similar to the luteinizing hormone. As well as, luteinizing hormone, gonadotropin gives a signal through the pituitary gland to the testicles to increase testosterone production. In addition to its ability to increase the production of testosterone, the drug improves the quality of sperm, can make more pronounced secondary sexual characteristics in both men and women. In women, the action of chorionic gonadotropin is to increase the production of progesterone and accelerates the maturation of the egg. It also contributes to the formation of the placenta.
In vivo, the amount of human chorionic gonadotropin is governed by feedback in the chain of interaction between the hypothalamus, pituitary, and testicles. Lack of hCG in the body leads to a decrease in size of the testicles and a decrease in their functionality. Artificial introduction of synthetic testosterone and its analogues gives the hypothalamus-pituitary-testes system to understand that the production of GnRH and gonadotropin is not required. Consequently, the testicles lose their function and decrease in size over time.
Possible side effects
The use of hCG can lead to the following negative effects:
- suppress the production of gonadotropin-releasing hormone;
- provoke dysfunction of the hypothalamus-pituitary-testes chain;
- lead to gynecomastia and masculinization;
- cause acne;
- cause afforestation and increase body hairiness;
- enlarge the prostate in size.
Dosing regimen
If we talk about how much HGG needs to be administered, then I can only give approximate recommendations. For example, the well-known Bill Phillips advises taking 4000 IU (International Units) a week for two to three weeks. However, there are other recommendations, according to which the reception of CGG should be approached individually, based on such a long steroid course, the course, how high the dosage was and what drugs were used. And if, for example, the basis of your steroid menu was “methane” and sustanon, then in this case the dosage of CGG should be higher.
Another question is how often to inject gonadotropin. One of the favorite models of Russian bodybuilders is the option in which 1000-1500 IU of gonadotropin is introduced every second day. On the other hand, according to the research of scientists, a single injection of CHG about 1500 IU increases the level of plasma testosterone by 250-300% and this level lasts for several days (up to five or six). Therefore, it is possible that more rare injections would be more appropriate, say, every five days. If we talk about the period during which one should “sit” on gonadotropin, then here almost all sources are unanimous: no more than three, maximum four weeks.